Massive intravascular haemolysis due toClostridium perfringens

Massive intravascular haemolysis due to Clostridium perfringens

Massive intravascular haemolysis due to mitral Björk-Shiley paraprosthetic regurgitation.

A 68-year-old man, who had undergone closed valvotomy for mitral stenosis in 1966, was admitted with restenosis of the mitral valve, which was confirmed by cardiac catheterisation. On 15 December 1975 a densely calcified mitral valve was excised and replaced by a 27 mm BjorkShiley prosthesis, which was fixed in place with interrupted Ethiflex sutures. The calcification extended into the mitral ...

Clostridium perfringens liver abscess with massive haemolysis.

Liver abscesses are commonly caused by Enterobacteriaceae and anaerobes. This report is of a patient with liver abscess with massive haemolysis and multiorgan failure caused by Clostridium perfringens. Despite the reportedly high mortality rate and poor prognostic factors, the patient eventually recovered with prompt treatment.

Clostridium perfringens septicaemia with massive intravascular haemolysis: a case report and review of the literature.

We describe the case of a 74-year-old man with cholangitis, complicated by Clostridium perfringens septicaemia and massive intravascular haemolysis. Clostridium perfringens septicaemia is a rare but well-known cause of massive intravascular haemolysis. Here we review 40 similar cases published since 1990. Most cases involve immunocompromised patients with underlying haematological disorder (22....

Massive intravascular hemolysis with organ failure due to Clostridium perfringens: evidence of intracytoplasmic C. perfringens.

A 66-year-old diabetic man presented with breathlessness, vomiting, and fever. His initial blood count demonstrated hemoglobin 135 g/L (130-175), platelets 155 3 10/L (150-400), and white blood cells 18.3 3 10/L (4-11). His hemoglobin fell rapidly over 6 hours to 44 g/L, platelets fell to 39 3 10/L, and white blood cells increased to 20.4 3 10/L. D-Dimer assay was 35 857 ng/mL (,250), fibrinoge...